Major Milestone & Progress Updates |
We are excited to announce the opening of our inaugural Mātai building on April 19. All are welcome to join us for celebration.
Download a copy of the Mātai Progress Update, which highlights key achievements over the past 3-years, and provides a snapshot of all the projects we are working on.
Mātai Scientific Advisory Board Member Emeritus Professor Graeme Bydder was formally awarded his Companion of New Zealand Order of Merit (CNZM) this month in the investiture ceremony. Graeme also released a new book 'MRI of Short and Ultrashort T2 Tissues – Making the Invisible Visible'. Mātai team members contributed to chapters.
Four international journal papers were published recently with the Mātai team and collaborators.
Congratulations to Associate Professor Miriam Scadeng – Principal Investigator of Mātai Meth Recovery study. Miriam has been appointed as the new Head of the Department of Anatomy and Medical Imaging at FMHS at the University of Auckland. Miriam's wealth of experience as a clinically trained radiologist and her passion for advancing medical imaging make such a perfect fit for this role. In the news, Tuta Ngarimu's legacy lives on, find out more about our recent scholarship students and summer interns, and internationally recognised neuroscientist, Sir Richard Faull shares his story on his roots in Taranaki. Ngā mihi nui, The Mātai Team |
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Mātai Building Opening Schedule |
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Join us in the morning for a pōwhiri to celebrate the opening of the inaugural Mātai building. In the afternoon, hear presentations about our latest projects, and explore the building. Don't miss our art exhibition by local artists and tamariki! It's a day to connect and celebrate, as we invite everyone to drop by at any time throughout the day. |
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MRI of short and ultrashort-T2 tissues – Making the Invisible Visible |
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From left to right: Emeritus Professor Graeme Bydder, Dr Samantha Holdsworth, Paul Condron, Dr Daniel Cornfeld. |
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A new textbook guide has been published by Emeritus Professor Graeme Bydder and Professor Jiang Du. The book, for physicists and radiologists, has chapter contributions by Paul Condron and Dr Daniel Cornfeld of the Mātai team. This book represents a labour of love, and is an exciting new contribution to understanding MRI contrast and improving many of our research projects. |
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New Insights on Grinkers' Myelinopathy/Delayed Post-Hypoxic Leukoencephalopathy (DPHL) |
Comparison of traditional T2-FLAIR images (upper row) and Mātai's new technique narrow mD dSIR images (lower row). No abnormality is seen on the T2-FLAIR image, but there are extensive areas of a high signal (possible damage) in the white matter of the brain on the dSIR images. |
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Led by Emeritus Professor Graeme Bydder, the paper suggests that DPHL could be far more common than previously thought, potentially going undiagnosed with conventional clinical and MRI criteria. The disorder is caused by oxygen deprivation to the brain, such as near-drowning, asphyxia, cardiac arrest, carbon monoxide poisoning, electrocution, and drug overdoses. Symptoms can occur days, weeks or months after the incident.
This revelation comes at a time when drug overdoses and the opioid crisis have reached epidemic proportions, suggesting that with the right imaging MR imaging sequence such as dSIR, brain damage in the form of Grinker's will be increasingly recognised.
Identifying such brain damage in patients is crucial for understanding their disease and treating it appropriately. This study underscores the importance of using advanced imaging techniques to determine the nature of patients' neurological and psychiatric conditions. For anyone interested in the evolving landscape of neurological disorders and the role of advanced imaging in uncovering a larger spectrum of brain injuries, this paper is a must-read. |
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Integration of DTI Parameters with Mesh Morphing and PCA for In Depth Analysis of While Matter Fibre Tracts |
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Maryam Tayebi explains the new modelling technique (video above).
The study, first authored by Dr Maryam Tayebi (Hugh & Moira Green Research Fellow at Mātai), under the leadership of Dr Vickie Shim at the Auckland Bioengineering Institute (ABI) and Principal Investigator at Mātai, presents a novel method for the analysis of brain white matter tracts.
A significant advantage of this method is its sensitivity to individual variations, enhancing the potential for early detection of brain changes. Researchers could, in the future, visualise the entire white matter tract's microstructure, identifying patterns of degeneration or injury that might be missed with conventional methods. This holds promise for refining diagnostic and predictive models for brain injuries in athletes through early detection or tailored treatment strategies. The implications of this research could extend to various fields, including neurology, sports medicine, and cognitive science, offering a new lens through which to examine the brain's intricate architecture and its resilience to physical trauma. |
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| Person Specific 3D model of the 3-D of the corticospinal tract (left). This and related TBI studies are made possible thanks to the support of Hugh Green
Foundation, Catalyst: Strategic Fund MBIE, New Zealand Health Research Council Explorer, Kānoa – Regional Economic Development & Investment Unit, Royal Society Catalyst, Te Tītoki Mataora Research Acceleration Programme, Neurological Foundation of New Zealand, New Zealand Rugby Foundation, Vision Research Foundation, Trust Tairāwhiti, Fred Lewis Enterprise Foundation, University of Auckland, an anonymous
donor, Mangatawa Beale Williams Memorial Trust, and JN & HB Williams Foundation. |
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Intracranial Aneurysm Wall Displacement Depicted by Amplified Flow Predicts Growth |
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The paper Intracranial aneurysm wall displacement depicted by amplified Flow predicts growth published with our collaborators Professor Kambiz Nael (UCLA), Dr Aymeric Pionteck, and Associate Professor Mehmet Kurt (University of Washington) introduces a novel method that amplifies brain aneurysm wall displacement to predict aneurysm growth. Called aFlow, the method builds on the amplified MRI (aMRI) technique that is being developed by Mātai and collaborators.
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Image of a brain aneurysm (right). Using the aFlow method, displacement is enhanced and depicted in various colours. This enhancement of aneurysm wall motion holds potential for the differentiation between stable and expanding aneurysms |
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Tuta Ngarimu's Tireless Advocacy to Create a Meth Free Tairāwhiti Lives On |
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Top Neurologist Sir Richard Faull Still Calls Taranaki Home |
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Mātai Interns and Scholarship Students: Nurturing Future Leaders
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Te Whatu Ora Tairāwhiti Talks
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Our thanks go out to Dr Bill Weiderman and Dr Saralyn MacKenzie who welcomed us back to the Gisborne Hospital Grand Rounds (centred around education, interdisciplinary collaboration, and clinical discussion) – where Dr Hari Kumar, Dr Josh McGeown, and Leigh Potter spoke about Mātai research projects and potential synergies with the Hospital. |
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The Mātai 3-Tesla MRI transitioning from its current location at Te Whatu Ora Tairāwhiti to its new premises on the Mātai campus site. We extend our heartfelt gratitude to Te Whatu Ora Tairāwhiti for accommodating us – we eagerly anticipate ongoing collaborations with the exceptional clinicians and healthcare professionals we've encountered along our journey. |
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| Emeritus Professor Graeme Bydder - CNZM |
Emeritus Professor Graeme Bydder with Kaumātua Joe Harawira (QSM) at his CNZM investiture ceremony in Christchurch on 19 March. Well-deserved recognition for one of the 'Godfathers' of MRI. Much of the technology behind the 100 million or more clinical scans done globally every year has been influenced by Graeme's work, which impacts the health of many across the world.
We were privileged to have Graeme visit us again at Mātai. He shared with the team presentations and insights on 'Ultra-high contrast MRI' and had a packed schedule discussing novel applications of his and the team's MRI methods with Mātai researchers. |
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"Hello, I'm Dineo. Originally from South Africa, my family relocated to New Zealand, where I completed high school in Whangarei. My journey led me to Auckland, where I completed medical school. Presently, I am working as a research fellow for the Auckland Eye Institute and Mātai.
In early April of this year, I visited Gisborne for the first time. There, I had the pleasure of meeting the remarkable team at Mātai and witnessed the astounding work being undertaken. Now, I am thrilled to be a part of the team and I am involved in the "Hole in the Head" project, where we hope to develop a non invasive technique to measure brain pressure. It's an exciting endeavour that holds the potential to revolutionise neurological diagnostics."
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Associate Professor Flavio Dell'Acqua |
It was a pleasure to host Associate Professor Flavio Dell' Acqua, Kings College, London, on his second visit to Mātai, to discuss a number of collaborative research projects involving advanced MRI. Flavio is a biomedical engineer, neuroscientist, and a leading researcher in the development and application of diffusion imaging to understand brain connections in relation to neurological and psychiatric disorders. | | |
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We enjoyed a visit from Manuela Zimmer, a PhD student at the University of Stuttgart, Germany. Her research focuses on skeletal muscle mechanics using both experimental and computational approaches. She has been collaborating with Dr Geoffrey Handsfield and his team at the Auckland Bioengineering Institute on her project. Manuela's goal is to develop a finite element model of the lower leg muscles. During her visit, she acquired various novel MRI sequences at Mātai to extract muscle shape, muscle fiber architecture, and connective tissue. In recent months, she has worked closely with Dr Handsfield, his team, and the Matai team to optimise MRI sequences, identifying several challenges in diffusion imaging of skeletal muscles.
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We would like to acknowledge, with appreciation, our supporters who made the establishment of Mātai possible, including Kānoa - RDU, Hugh Green Foundation, Trust Tairāwhiti, the Mangatawa Beale Williams Memorial Trust, the JN and HB Williams Foundation, the University of Auckland, GE Healthcare, Peter and Bronwen Holdsworth Family, Pultron Composites Limited, the Lotteries Significant Projects Fund, Fred Lewis Enterprise Foundation, Anonymous Donor, the QUEST Trust, Turanga Health, Friends of Mātai, local iwi, and many others.
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